PDBe 5w9q

X-ray diffraction
1.8Å resolution

Zinc finger region of MBD1 in complex with CpG DNA


Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct DNA molecule
Macromolecules (2 distinct):
Methyl-CpG-binding domain protein 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 60 amino acids
Theoretical weight: 7 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: Q9UIS9 (Residues: 330-388; Coverage: 10%)
Gene names: CXXC3, MBD1, PCM1
Sequence domains: CXXC zinc finger domain
dna Chains: C, D, E, F
Molecule details ›
Chains: C, D, E, F
Length: 12 nucleotides
Theoretical weight: 3.66 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CLSI BEAMLINE 08ID-1
Spacegroup: C2
Unit cell:
a: 139.339Å b: 27.8Å c: 64.914Å
α: 90° β: 106.52° γ: 90°
R R work R free
0.228 0.226 0.253
Expression systems:
  • Escherichia coli
  • Not provided