5vww

X-ray diffraction
2.8Å resolution

Bak core latch dimer in complex with Bim-RT - Tetragonal

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Bcl-2 homologous antagonist/killer Chains: A, B
Molecule details ›
Chains: A, B
Length: 170 amino acids
Theoretical weight: 19.04 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q16611 (Residues: 23-186; Coverage: 78%)
  • Best match: Q16611-2 (Residues: 23-116)
Gene names: BAK, BAK1, BCL2L7, CDN1
Sequence domains: Apoptosis regulator proteins, Bcl-2 family
Bcl-2-like protein 11 Chains: C, D
Molecule details ›
Chains: C, D
Length: 26 amino acids
Theoretical weight: 3.18 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: O43521 (Residues: 141-166; Coverage: 13%)
Gene names: BCL2L11, BIM

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX2
Spacegroup: P43212
Unit cell:
a: 87.79Å b: 87.79Å c: 95.46Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.23 0.224 0.281
Expression systems:
  • Escherichia coli
  • Not provided