PDBe 5vb9

X-ray diffraction
1.7Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Interleukin-17A Chains: A, B
Molecule details ›
Chains: A, B
Length: 119 amino acids
Theoretical weight: 13.75 KDa
Source organism: Homo sapiens
Expression system: Baculovirus expression vector pFastBac1-HM
UniProt:
  • Canonical: Q16552 (Residues: 38-155; Coverage: 89%)
Gene names: CTLA8, IL17, IL17A
Sequence domains: Interleukin-17
Peptide inhibitor Chains: C, D
Molecule details ›
Chains: C, D
Length: 15 amino acids
Theoretical weight: 1.85 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 31-ID
Spacegroup: P21212
Unit cell:
a: 36.771Å b: 55.122Å c: 143.953Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.183 0.182 0.211
Expression systems:
  • Baculovirus expression vector pFastBac1-HM
  • Not provided