5utz

X-ray diffraction
2.75Å resolution

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-158043 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Ig-like domain-containing protein Chains: B, F, H, J
Molecule details ›
Chains: B, F, H, J
Length: 224 amino acids
Theoretical weight: 23.76 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q6GMX6 (Residues: 20-49, 50-120, 121-238; Coverage: 49%)
Gene name: IGH@
Sequence domains:
Ig-like domain-containing protein Chains: C, G, K, L
Molecule details ›
Chains: C, G, K, L
Length: 216 amino acids
Theoretical weight: 23.11 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q6IPQ0 (Residues: 23-86, 87-236; Coverage: 97%)
Gene name: IGL@
Sequence domains:
Structure domains: Immunoglobulins
Interleukin-2 Chains: A, D, E, I
Molecule details ›
Chains: A, D, E, I
Length: 133 amino acids
Theoretical weight: 15.44 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
  • Canonical: P60568 (Residues: 21-153; Coverage: 100%)
Gene name: IL2
Sequence domains: Interleukin 2
Structure domains: Growth Hormone; Chain: A;

Ligands and Environments

1 bound ligand:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.1
Spacegroup: P21
Unit cell:
a: 86.01Å b: 145.73Å c: 107.32Å
α: 90° β: 95.38° γ: 90°
R-values:
R R work R free
0.194 0.192 0.248
Expression systems:
  • Homo sapiens
  • Trichoplusia ni