5ug0

X-ray diffraction
3.4Å resolution

Human antibody H2897 in complex with influenza hemagglutinin H1 Solomon Islands/03/2006

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dodecamer (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
Hemagglutinin HA1 chain Chain: A
Molecule details ›
Chain: A
Length: 327 amino acids
Theoretical weight: 36.51 KDa
Source organism: Influenza A virus (A/Solomon Islands/3/2006(H1N1))
Expression system: Trichoplusia ni
UniProt:
  • Canonical: A7UPX0 (Residues: 18-343; Coverage: 58%)
Gene name: HA
Hemagglutinin HA2 chain Chain: B
Molecule details ›
Chain: B
Length: 182 amino acids
Theoretical weight: 20.82 KDa
Source organism: Influenza A virus (A/Solomon Islands/3/2006(H1N1))
Expression system: Trichoplusia ni
UniProt:
  • Canonical: A7UPX0 (Residues: 344-519; Coverage: 31%)
Gene name: HA
2897 light chain Chain: C
Molecule details ›
Chain: C
Length: 216 amino acids
Theoretical weight: 23.53 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
2897 heavy chain Chain: D
Molecule details ›
Chain: D
Length: 232 amino acids
Theoretical weight: 24.54 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-E
Spacegroup: P321
Unit cell:
a: 142.2Å b: 142.2Å c: 200.41Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.242 0.24 0.278
Expression systems:
  • Trichoplusia ni
  • Homo sapiens