PDBe 5tvq

X-ray diffraction
2.35Å resolution

Mouse Tdp2 catalytic domain bound to SUMO2

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Tyrosyl-DNA phosphodiesterase 2 Chain: A
Molecule details ›
Chain: A
Length: 256 amino acids
Theoretical weight: 28.91 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9JJX7 (Residues: 118-370; Coverage: 68%)
Gene names: Tdp2, Ttrap
Sequence domains: Endonuclease/Exonuclease/phosphatase family
Small ubiquitin-related modifier 2 Chain: B
Molecule details ›
Chain: B
Length: 86 amino acids
Theoretical weight: 9.84 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P61957 (Residues: 10-93; Coverage: 88%)
Gene names: Smt3b, Smt3h2, Sumo2
Sequence domains: Ubiquitin-2 like Rad60 SUMO-like

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P64
Unit cell:
a: 106.838Å b: 106.838Å c: 56.585Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.188 0.186 0.231
Expression system: Escherichia coli