X-ray diffraction
2.55Å resolution

A. aeolicus BioW with AMP-CPP and pimelate


Function and Biology Details

Reaction catalysed:
ATP + 6-carboxyhexanoate + CoA = AMP + diphosphate + 6-carboxyhexanoyl-CoA
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
6-carboxyhexanoate--CoA ligase Chains: A, B
Molecule details ›
Chains: A, B
Length: 240 amino acids
Theoretical weight: 27.45 KDa
Source organism: Aquifex aeolicus
Expression system: Escherichia coli
  • Canonical: O67575 (Residues: 1-240; Coverage: 100%)
Gene names: aq_1659, bioW
Sequence domains: 6-carboxyhexanoate--CoA ligase

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-F
Spacegroup: P212121
Unit cell:
a: 68.576Å b: 106.381Å c: 113.553Å
α: 90° β: 90° γ: 90°
R R work R free
0.187 0.184 0.229
Expression system: Escherichia coli