Electron Microscopy
4.4Å resolution

Structure of rabbit RyR1 (Caffeine/ATP/EGTA dataset, all particles)

Related structures: EMD-8381

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero octamer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Peptidyl-prolyl cis-trans isomerase FKBP1B Chains: A, F, H, J
Molecule details ›
Chains: A, F, H, J
Length: 108 amino acids
Theoretical weight: 11.8 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: P68106 (Residues: 1-108; Coverage: 100%)
Gene names: FKBP12.6, FKBP1B, FKBP1L, FKBP9, OTK4
Sequence domains: FKBP-type peptidyl-prolyl cis-trans isomerase
Ryanodine receptor 1 Chains: B, E, G, I
Molecule details ›
Chains: B, E, G, I
Length: 4416 amino acids
Theoretical weight: 475.11 KDa
Source organism: Oryctolagus cuniculus
  • Canonical: P11716 (Residues: 12-5037; Coverage: 88%)
Gene name: RYR1
Sequence domains:

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 4.4Å
Relevant EMDB volumes: EMD-8381
Expression system: Escherichia coli