› 5szr

X-ray diffraction
2.3Å resolution

Protocadherin Gamma B2 extracellular cadherin domains 3-6

Released:
DOI: 10.2210/pdb5szr/pdb
PDB entry 5szr coloured by chain, front view.
PDB entry 5szr coloured by chain, side view.
PDB entry 5szr coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
γ-Protocadherin structural diversity and functional implications.
Goodman KM, Rubinstein R, Thu CA, Mannepalli S, Bahna F, Ahlsén G, Rittenhouse C, Maniatis T, Honig B, Shapiro L
Elife 5 (2016)
PMID: 27782885

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-187599 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (4 distinct):
Cadherin domain-containing protein Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 441 amino acids
Theoretical weight: 48.18 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
UniProt:
  • Canonical: Q91XX7 (Residues: 237-669; Coverage: 48%)
Gene name: Pcdhgb2
Sequence domains: Cadherin domain

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, FUC
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG, FUC
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG, FUC
Carbohydrate polymer
3 bound ligands:
Ligand CA 27 x CA
Ligand MAN 21 x MAN
Ligand EDO 5 x EDO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: P41212
Unit cell:
a: 104.755Å b: 104.755Å c: 352.136Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.251 0.25 0.278
Expression system: Homo sapiens

Quick links

Citations

12 review citations

Regulation of neural circuit formation by protocadherins.
Peek et al. (2017)
11 more

5 mentions without citation

γ-Protocadherin structural diversity and functional implications.
Goodman et al. (2016)
4 more