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Hybrid

STRUCTURE OF BOVINE PANCREATIC TRYPSIN INHIBITOR. RESULTS OF JOINT NEUTRON AND X-RAY REFINEMENT OF CRYSTAL FORM II

Released:
DOI: 10.2210/pdb5pti/pdb
PDB 5pti coloured by chain and viewed from the front.
PDB 5pti coloured by chain and viewed from the side.
PDB 5pti coloured by chain and viewed from the top.
Source organism: Bos taurus
Primary publication:
Structure of bovine pancreatic trypsin inhibitor. Results of joint neutron and X-ray refinement of crystal form II.
Wlodawer A, Walter J, Huber R, Sjölin L
J. Mol. Biol. 180 301-29 (1984)
PMID: 6210373

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Pancreatic trypsin inhibitor Chain: A
Molecule details ›
Chain: A
Length: 58 amino acids
Theoretical weight: 6.53 KDa
Source organism: Bos taurus
Expression system: Not provided
UniProt:
  • Canonical: P00974 (Residues: 36-93; Coverage: 73%)
Sequence domains: Kunitz/Bovine pancreatic trypsin inhibitor domain
Structure domains: Pancreatic trypsin inhibitor Kunitz domain

Ligands and Environments

3 bound ligands:
Ligand PO4 1 x PO4
Ligand UNX 1 x UNX
Ligand DOD 63 x DOD
No modified residues

Experiments and Validation Details

Experimental Method: Neutron Diffraction, X-ray diffraction
Spacegroup: P212121
Unit cell:
a: 74.1Å b: 23.4Å c: 28.9Å
α: 90° β: 90° γ: 90°
Expression system: Not provided

Quick links

Citations

17 review citations

Inverse statistical physics of protein sequences: a key issues review.
Cocco et al. (2018)
16 more

62 mentions without citation

Evaluation of models determined by neutron diffraction and proposed improvements to their validation and deposition.
Liebschner et al. (2018)
61 more