PDBe 5oh2

X-ray diffraction
1.9Å resolution

Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with Pyrrolidin-2-one (Butyrolactam)


Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
CULT domain-containing protein Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 125 amino acids
Theoretical weight: 13.7 KDa
Source organism: Magnetospirillum gryphiswaldense
Expression system: Escherichia coli
  • Canonical: A4TVL0 (Residues: 1-124; Coverage: 100%)
Gene name: MGR_0879

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: P212121
Unit cell:
a: 56.911Å b: 59.686Å c: 88.443Å
α: 90° β: 90° γ: 90°
R R work R free
0.179 0.177 0.225
Expression system: Escherichia coli