X-ray diffraction
2.58Å resolution

Crystal Structure of human Pro-myostatin Precursor at 2.6 A Resolution


Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Growth/differentiation factor 8 Chains: A, B
Molecule details ›
Chains: A, B
Length: 335 amino acids
Theoretical weight: 37.88 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
  • Canonical: O14793 (Residues: 43-375; Coverage: 95%)
Gene names: GDF8, MSTN
Sequence domains: Transforming growth factor beta like domain

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: C2
Unit cell:
a: 168.157Å b: 36.301Å c: 120.448Å
α: 90° β: 104.39° γ: 90°
R R work R free
0.217 0.215 0.26
Expression system: Escherichia coli BL21(DE3)