PDBe 5nlx

X-ray diffraction
2.14Å resolution

A2A Adenosine receptor room-temperature structure determined by serial millisecond crystallography

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Adenosine receptor A2a; Soluble cytochrome b562 Chain: A
Molecule details ›
Chain: A
Length: 433 amino acids
Theoretical weight: 48 KDa
Source organisms: Expression system: Trichoplusia ni
UniProt:
  • Canonical: P0ABE7 (Residues: 23-127; Coverage: 99%)
  • Canonical: P29274 (Residues: 2-208, 219-317; Coverage: 74%)
  • nullnull
Gene names: ADORA2, ADORA2A, cybC
Sequence domains: 7 transmembrane receptor (rhodopsin family)

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: C2221
Unit cell:
a: 40.33Å b: 180.07Å c: 142.66Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.2 0.199 0.229
Expression system: Trichoplusia ni