PDBe 5ncp

X-ray diffraction
1.65Å resolution

ENAH EVH1 in complex with Ac-[2-Cl-F]-[ProM-2]-[ProM-12]-OH

Released:
Source organism: Homo sapiens
Entry authors: Barone M, Roske Y

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein enabled homolog Chain: A
Molecule details ›
Chain: A
Length: 113 amino acids
Theoretical weight: 12.63 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'
UniProt:
  • Canonical: Q8N8S7 (Residues: 1-111; Coverage: 19%)
Gene names: ENAH, MENA
Sequence domains: WH1 domain

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.1
Spacegroup: C222
Unit cell:
a: 44.141Å b: 141.367Å c: 34.706Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.186 0.184 0.208
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'