5mlz

X-ray diffraction
2Å resolution

Dolichyl phosphate mannose synthase in complex with GDP and Mg2+

Released:
Source organism: Pyrococcus furiosus DSM 3638
Primary publication:
Structural basis for dolichylphosphate mannose biosynthesis.
OpenAccess logo Nat Commun 8 120 (2017)
PMID: 28743912

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Dolichol monophosphate mannose synthase Chain: A
Molecule details ›
Chain: A
Length: 374 amino acids
Theoretical weight: 42.68 KDa
Source organism: Pyrococcus furiosus DSM 3638
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8U4M3 (Residues: 1-352; Coverage: 100%)
Gene name: PF0058
Sequence domains:

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SOLEIL BEAMLINE PROXIMA 1
Spacegroup: C2221
Unit cell:
a: 90.87Å b: 146.21Å c: 95.35Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.242 0.241 0.257
Expression system: Escherichia coli