X-ray diffraction
2.45Å resolution

Crystal structure of human PCNA in complex with ZRANB3 APIM motif peptide


Function and Biology Details

Structure analysis Details

Assemblies composition:
homo trimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Proliferating cell nuclear antigen Chains: A, C, E
Molecule details ›
Chains: A, C, E
Length: 261 amino acids
Theoretical weight: 28.8 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: P12004 (Residues: 1-261; Coverage: 100%)
Gene name: PCNA
Sequence domains:
DNA annealing helicase and endonuclease ZRANB3 Chains: B, D, F
Molecule details ›
Chains: B, D, F
Length: 11 amino acids
Theoretical weight: 1.27 KDa
Source organism: Homo sapiens
Expression system: Not provided
  • Canonical: Q5FWF4 (Residues: 1069-1079; Coverage: 1%)
Gene name: ZRANB3

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P3121
Unit cell:
a: 84.631Å b: 84.631Å c: 201.77Å
α: 90° β: 90° γ: 120°
R R work R free
0.223 0.221 0.264
Expression systems:
  • Escherichia coli
  • Not provided