5mlo

X-ray diffraction
1.96Å resolution

Crystal structure of human PCNA in complex with ZRANB3 PIP box peptide

Released:

Function and Biology Details

Structure analysis Details

Assemblies composition:
homo trimer (preferred)
monomeric
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Proliferating cell nuclear antigen Chains: A, C, E
Molecule details ›
Chains: A, C, E
Length: 261 amino acids
Theoretical weight: 28.8 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P12004 (Residues: 1-261; Coverage: 100%)
Gene name: PCNA
Sequence domains:
DNA annealing helicase and endonuclease ZRANB3 Chains: B, D, F
Molecule details ›
Chains: B, D, F
Length: 15 amino acids
Theoretical weight: 1.89 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q5FWF4 (Residues: 515-529; Coverage: 1%)
Gene name: ZRANB3

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: P212121
Unit cell:
a: 68.136Å b: 86.802Å c: 156.679Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.214 0.211 0.259
Expression systems:
  • Escherichia coli
  • Not provided