X-ray diffraction
1.8Å resolution

Function and Biology Details

Reaction catalysed:
UDP-sugar + H(2)O = UMP + alpha-D-aldose 1-phosphate
Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Uridine diphosphate glucose pyrophosphatase NUDT22 Chains: A, B
Molecule details ›
Chains: A, B
Length: 330 amino acids
Theoretical weight: 35.53 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
  • Canonical: Q9BRQ3 (Residues: 1-303; Coverage: 100%)
Gene names: NUDT22, PP11246

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.1
Spacegroup: P21
Unit cell:
a: 52.213Å b: 46.871Å c: 119.606Å
α: 90° β: 93.92° γ: 90°
R R work R free
0.201 0.199 0.242
Expression system: Escherichia coli BL21(DE3)