5l2u

X-ray diffraction
2.28Å resolution

Oligomer crystal structure of CC chemokine 5 (CCL5)

Released:
Source organism: Homo sapiens
Entry authors: Liang W, Wang A, Tang W-J

Function and Biology Details

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
C-C motif chemokine 5 Chains: A, B, C, D, E, F, G, H, I
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I
Length: 65 amino acids
Theoretical weight: 7.51 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P13501 (Residues: 27-91; Coverage: 96%)
Gene names: CCL5, D17S136E, SCYA5
Sequence domains: Small cytokines (intecrine/chemokine), interleukin-8 like

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: C222
Unit cell:
a: 121.799Å b: 210.082Å c: 126.718Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.179 0.178 0.209
Expression system: Escherichia coli