PDBe 5l1x

X-ray diffraction
3.3Å resolution

Structure of the Human Metapneumovirus Fusion Protein in the Postfusion Conformation

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Fusion glycoprotein F0 Chains: A, C, E, G, I, K
Molecule details ›
Chains: A, C, E, G, I, K
Length: 89 amino acids
Theoretical weight: 10.19 KDa
Source organism: Human metapneumovirus
Expression system: Chlorocebus aethiops
UniProt:
  • Canonical: Q91F55 (Residues: 19-101; Coverage: 15%)
Gene name: F
Fusion glycoprotein F0 Chains: B, D, F, H, J, L
Molecule details ›
Chains: B, D, F, H, J, L
Length: 387 amino acids
Theoretical weight: 42.06 KDa
Source organism: Human metapneumovirus
Expression system: Chlorocebus aethiops
UniProt:
  • Canonical: Q91F55 (Residues: 112-489; Coverage: 70%)
Gene name: F

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P41212
Unit cell:
a: 128.72Å b: 128.72Å c: 572.79Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.223 0.22 0.27
Expression system: Chlorocebus aethiops