5kue

X-ray diffraction
1.5Å resolution

Human SeMet incorporated I141M/L146M mitochondrial calcium uniporter (residues 72-189) crystal structure with magnesium

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Calcium uniporter protein, mitochondrial Chain: A
Molecule details ›
Chain: A
Length: 124 amino acids
Theoretical weight: 14.01 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8NE86 (Residues: 72-189; Coverage: 34%)
Gene names: C10orf42, CCDC109A, MCU

Ligands and Environments

3 bound ligands:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: CLSI BEAMLINE 08ID-1
Spacegroup: P65
Unit cell:
a: 55.5Å b: 55.5Å c: 69.02Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.202 0.2 0.212
Expression system: Escherichia coli