PDBe 5kmg

Electron Microscopy
3.5Å resolution

Near-atomic cryo-EM structure of PRC1 bound to the microtubule

Released:
Source organisms:
Related structures: EMD-8266

Function and Biology Details

Structure analysis Details

Assemblies composition:
hetero 42-mer (preferred)
hetero trimer
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Tubulin alpha-1B chain Chain: A
Molecule details ›
Chain: A
Length: 441 amino acids
Theoretical weight: 49.1 KDa
Source organism: Sus scrofa
UniProt:
  • Canonical: Q2XVP4 (Residues: 1-441; Coverage: 98%)
Gene name: TUBA1B
Sequence domains:
Structure domains:
Tubulin beta chain Chain: B
Molecule details ›
Chain: B
Length: 431 amino acids
Theoretical weight: 48.3 KDa
Source organism: Sus scrofa
UniProt:
  • Canonical: P02554 (Residues: 1-431; Coverage: 97%)
Sequence domains:
Structure domains:
Protein regulator of cytokinesis 1 Chain: P
Molecule details ›
Chain: P
Length: 128 amino acids
Theoretical weight: 15.69 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O43663 (Residues: 341-464; Coverage: 20%)
Gene name: PRC1
Structure domains: Methane Monooxygenase Hydroxylase; Chain G, domain 1

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.5Å
Relevant EMDB volumes: EMD-8266
Expression system: Escherichia coli