PDBe 5kiz

Solution NMR

Solution Structure of a repacked version of HIF-2 alpha PAS-B

Released:
Source organism: Homo sapiens
Entry authors: Correa F, Key J, Kuhlman B, Gardner KH

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Endothelial PAS domain-containing protein 1 Chain: A
Molecule details ›
Chain: A
Length: 114 amino acids
Theoretical weight: 13.26 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q99814 (Residues: 239-349; Coverage: 13%)
Gene names: BHLHE73, EPAS1, HIF2A, MOP2, PASD2
Sequence domains: PAS fold
Structure domains: Beta-Lactamase

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 91%
Refinement method: torsion angle dynamics
Chemical shifts: BMR30118  
Expression system: Escherichia coli