5k81

X-ray diffraction
2.01Å resolution

Crystal Structure of a Primate APOBEC3G N-Terminal Domain

Released:
Source organism: Macaca mulatta
Primary publication:
Crystal structures of APOBEC3G N-domain alone and its complex with DNA.
OpenAccess logo Nat Commun 7 12193 (2016)
PMID: 27480941

Function and Biology Details

Biochemical function:
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DNA dC->dU-editing enzyme APOBEC-3G Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 196 amino acids
Theoretical weight: 23.09 KDa
Source organism: Macaca mulatta
Expression system: Escherichia coli K-12
UniProt:
  • Canonical: M1GSK9 (Residues: 1-138, 147-195; Coverage: 49%)
Gene name: APOBEC3G
Sequence domains: Novel AID APOBEC clade 2

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.1
Spacegroup: P21
Unit cell:
a: 106.213Å b: 81.297Å c: 106.298Å
α: 90° β: 120.03° γ: 90°
R-values:
R R work R free
0.188 0.188 0.223
Expression system: Escherichia coli K-12