PDBe 5jv3

X-ray diffraction
2.01Å resolution

The neck-linker and alpha 7 helix of Homo sapiens Eg5 fused to EB1

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Kinesin-like protein KIF11; Microtubule-associated protein RP/EB family member 1 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 76 amino acids
Theoretical weight: 8.96 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q15691 (Residues: 210-257; Coverage: 18%)
  • Canonical: P52732 (Residues: 366-391; Coverage: 3%)
  • nullnull
Gene names: EG5, KIF11, KNSL1, MAPRE1, TRIP5
Sequence domains: EB1-like C-terminal motif

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P21
Unit cell:
a: 34.839Å b: 59.502Å c: 72.664Å
α: 90° β: 100.58° γ: 90°
R-values:
R R work R free
0.217 0.215 0.247
Expression system: Escherichia coli BL21(DE3)