› 5jmg

X-ray diffraction
1.85Å resolution

X-ray structure of the complex between bovine pancreatic ribonuclease and pentachlorocarbonyliridate(III) (4 days of soaking)

Released:
DOI: 10.2210/pdb5jmg/pdb
PDB entry 5jmg coloured by chain, front view.
PDB entry 5jmg coloured by chain, side view.
PDB entry 5jmg coloured by chain, top view.
Source organism: Bos taurus
Primary publication:
Mapping the protein-binding sites for iridium(iii)-based CO-releasing molecules.
Caterino M, Petruk AA, Vergara A, Ferraro G, Marasco D, Doctorovich F, Estrin DA, Merlino A
Dalton Trans 45 12206-14 (2016)
PMID: 27411388

Function and Biology Details

Reaction catalysed: 
(1a) an (RNA) containing cytidine = an (RNA)-3'-cytidine-2',3'-cyclophosphate + a 5'-hydroxy-ribonucleotide-3'-(RNA)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-158390 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ribonuclease pancreatic Chains: A, B
Molecule details ›
Chains: A, B
Length: 124 amino acids
Theoretical weight: 13.71 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P61823 (Residues: 27-150; Coverage: 100%)
Gene names: RNASE1, RNS1
Sequence domains: Pancreatic ribonuclease
Structure domains: Ribonuclease A-like domain

Ligands and Environments

3 bound ligands:
Ligand IR 5 x IR
Ligand CL 5 x CL
Ligand CMO 3 x CMO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007 HF
Spacegroup: C2
Unit cell:
a: 99.932Å b: 32.652Å c: 72.273Å
α: 90° β: 90.28° γ: 90°
R-values:
R R work R free
0.175 0.173 0.226

Quick links

Citations

6 citation in other articles

CO-independent modification of K+ channels by tricarbonyldichlororuthenium(II) dimer (CORM-2).
Gessner et al. (2017)
5 more