PDBe 5jds

X-ray diffraction
1.7Å resolution

Crystal structure of PD-L1 complexed with a nanobody at 1.7 Angstron resolution


Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Nanobody Chain: B
Molecule details ›
Chain: B
Length: 146 amino acids
Theoretical weight: 15.77 KDa
Source organism: Camelidae
Expression system: Homo sapiens
Structure domains: Immunoglobulins
Programmed cell death 1 ligand 1 Chain: A
Molecule details ›
Chain: A
Length: 124 amino acids
Theoretical weight: 14.34 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: Q9NZQ7 (Residues: 18-132; Coverage: 42%)
Gene names: B7H1, CD274, PDCD1L1, PDCD1LG1, PDL1
Sequence domains: Immunoglobulin V-set domain
Structure domains: Immunoglobulins

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL19U1
Spacegroup: P61
Unit cell:
a: 83.13Å b: 83.13Å c: 73.23Å
α: 90° β: 90° γ: 120°
R R work R free
0.18 0.178 0.204
Expression systems:
  • Homo sapiens
  • Escherichia coli