PDBe 5j5j

X-ray diffraction
3.29Å resolution

Crystal structure of a chimera of human Desmocollin-2 EC1 and human Desmoglein-2 EC2-EC5

Released:
Source organism: Homo sapiens

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Desmocollin-2; Desmoglein-2 Chain: A
Molecule details ›
Chain: A
Length: 557 amino acids
Theoretical weight: 62.69 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q02487 (Residues: 136-235; Coverage: 11%)
  • Canonical: Q14126 (Residues: 152-601; Coverage: 41%)
  • nullnull
Gene names: CDHF2, CDHF5, DSC2, DSC3, DSG2
Sequence domains: Cadherin domain

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Unit cell:
a: 63.494Å b: 87.489Å c: 218.536Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.249 0.247 0.285
Expression system: Homo sapiens