5j1s

X-ray diffraction
1.4Å resolution

TorsinA-LULL1 complex, H. sapiens, bound to VHH-BS2

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Torsin-1A Chain: A
Molecule details ›
Chain: A
Length: 284 amino acids
Theoretical weight: 32.74 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O14656 (Residues: 51-332; Coverage: 90%)
Gene names: DQ2, DYT1, TA, TOR1A, TORA
Torsin-1A-interacting protein 2 Chain: B
Molecule details ›
Chain: B
Length: 239 amino acids
Theoretical weight: 26.73 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8NFQ8 (Residues: 233-470; Coverage: 51%)
Gene names: IFRG15, LULL1, TOR1AIP2
Structure domains: Rossmann fold
VHH domain BS-2 Chain: C
Molecule details ›
Chain: C
Length: 123 amino acids
Theoretical weight: 13.3 KDa
Source organism: Vicugna pacos
Expression system: Escherichia coli
Structure domains: Immunoglobulins

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: P212121
Unit cell:
a: 75.739Å b: 90.659Å c: 105.092Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.144 0.143 0.188
Expression system: Escherichia coli