PDBe 5iz6

X-ray diffraction
2.15Å resolution

Protein-protein interaction


Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Adenomatous polyposis coli protein Chain: A
Molecule details ›
Chain: A
Length: 354 amino acids
Theoretical weight: 39.27 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: P25054 (Residues: 407-751; Coverage: 12%)
Gene names: APC, DP2.5
Sequence domains: Armadillo/beta-catenin-like repeat
Molecule details ›
Chain: B
Length: 9 amino acids
Theoretical weight: 902 Da
Source organism: Homo sapiens
Expression system: Not provided

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL19U1
Spacegroup: P21
Unit cell:
a: 51.396Å b: 63.215Å c: 52.768Å
α: 90° β: 95.61° γ: 90°
R R work R free
0.165 0.163 0.206
Expression systems:
  • Escherichia coli
  • Not provided