5iy4

X-ray diffraction
2.94Å resolution

Crystal structure of human PCNA in complex with the PIP box of DVC1

Released:
Primary publication:
Crystal structure of human PCNA in complex with the PIP box of DVC1.
Biochem. Biophys. Res. Commun. 474 264-70 (2016)
PMID: 27084448

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Proliferating cell nuclear antigen Chains: A, C, E
Molecule details ›
Chains: A, C, E
Length: 270 amino acids
Theoretical weight: 30.01 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P12004 (Residues: 1-261; Coverage: 100%)
Gene name: PCNA
Sequence domains:
Structure domains: Proliferating Cell Nuclear Antigen
SprT-like domain-containing protein Spartan Chains: B, D, F
Molecule details ›
Chains: B, D, F
Length: 16 amino acids
Theoretical weight: 1.85 KDa
Source organism: synthetic construct
Expression system: Not provided
UniProt:
  • Canonical: Q9H040 (Residues: 321-336; Coverage: 3%)
Gene names: C1orf124, DVC1, SPRTN, UNQ1880/PRO4323

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL18U1
Spacegroup: P43212
Unit cell:
a: 71.647Å b: 71.647Å c: 322.208Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.21 0.207 0.27
Expression systems:
  • Escherichia coli
  • Not provided