PDBe 5iu8

X-ray diffraction
2Å resolution

Crystal structure of stabilized A2A adenosine receptor A2AR-StaR2-bRIL in complex with compound 12f at 2.0A resolution

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Soluble cytochrome b562; Adenosine receptor A2a Chain: A
Molecule details ›
Chain: A
Length: 433 amino acids
Theoretical weight: 48 KDa
Source organisms: Expression system: Trichoplusia ni
UniProt:
  • Canonical: P0ABE7 (Residues: 23-128; Coverage: 100%)
  • Canonical: P29274 (Residues: 2-208, 219-315; Coverage: 74%)
  • nullnull
Gene names: ADORA2, ADORA2A, cybC
Sequence domains: Cytochrome b562

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I24
Spacegroup: C2221
Unit cell:
a: 39.312Å b: 179.537Å c: 139.994Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.182 0.181 0.2
Expression system: Trichoplusia ni