PDBe 5iu7

X-ray diffraction
1.9Å resolution

Crystal structure of stabilized A2A adenosine receptor A2AR-StaR2-bRIL in complex with compound 12c at 1.9A resolution


Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Soluble cytochrome b562; Adenosine receptor A2a Chain: A
Molecule details ›
Chain: A
Length: 433 amino acids
Theoretical weight: 48 KDa
Source organisms: Expression system: Trichoplusia ni
  • Canonical: P0ABE7 (Residues: 23-127; Coverage: 99%)
  • Canonical: P29274 (Residues: 2-208, 219-315; Coverage: 74%)
  • nullnull
Gene names: ADORA2, ADORA2A, cybC

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I24
Spacegroup: C2221
Unit cell:
a: 39.384Å b: 180.036Å c: 139.835Å
α: 90° β: 90° γ: 90°
R R work R free
0.172 0.17 0.198
Expression system: Trichoplusia ni