X-ray diffraction
1.23Å resolution

Nanobody targeting human Vsig4 in Spacegroup C2


Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Nanobody Chain: B
Molecule details ›
Chain: B
Length: 131 amino acids
Theoretical weight: 14.6 KDa
Source organism: Camelidae
Expression system: Escherichia coli
Structure domains: Immunoglobulins
V-set and immunoglobulin domain-containing protein 4 Chain: A
Molecule details ›
Chain: A
Length: 220 amino acids
Theoretical weight: 24.61 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: Q9Y279 (Residues: 19-232; Coverage: 56%)
Gene names: CRIg, UNQ317/PRO362, VSIG4, Z39IG
Sequence domains:
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL19U1
Spacegroup: C2
Unit cell:
a: 126.791Å b: 30.369Å c: 84.297Å
α: 90° β: 126.88° γ: 90°
R R work R free
0.172 0.172 0.185
Expression system: Escherichia coli