5gl1

Electron Microscopy
5.7Å resolution

Structure of RyR1 in an open state

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero octamer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Ryanodine receptor 1 Chains: A, C, E, G
Molecule details ›
Chains: A, C, E, G
Length: 5037 amino acids
Theoretical weight: 565.91 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: P11716 (Residues: 1-5037; Coverage: 100%)
Gene name: RYR1
Sequence domains:
Peptidyl-prolyl cis-trans isomerase FKBP1A Chains: B, D, F, H
Molecule details ›
Chains: B, D, F, H
Length: 108 amino acids
Theoretical weight: 11.97 KDa
Source organism: Oryctolagus cuniculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P62943 (Residues: 1-108; Coverage: 100%)
Gene names: FKBP1, FKBP12, FKBP1A
Sequence domains: FKBP-type peptidyl-prolyl cis-trans isomerase

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 5.7Å
Relevant EMDB volumes: EMD-9521
Expression system: Escherichia coli