PDBe 5g5p

Electron Microscopy
5.3Å resolution

Structure of the Saccharomyces cerevisiae TREX-2 complex

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
Nuclear mRNA export protein SAC3 Chain: A
Molecule details ›
Chain: A
Length: 805 amino acids
Theoretical weight: 93.21 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P46674 (Residues: 1-805; Coverage: 62%)
Gene names: LEP1, SAC3, YD8358.13, YDR159W
Sequence domains:
NUCLEAR MRNA EXPORT PROTEIN SAC3 Chains: D, E, F
Molecule details ›
Chains: D, E, F
Length: 805 amino acids
Theoretical weight: 68.53 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Spodoptera frugiperda
Nuclear mRNA export protein THP1 Chain: B
Molecule details ›
Chain: B
Length: 455 amino acids
Theoretical weight: 52.73 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q08231 (Residues: 1-455; Coverage: 100%)
Gene names: BUD29, O1140, THP1, YOL072W
Sequence domains: PCI domain
26S proteasome complex subunit SEM1 Chain: C
Molecule details ›
Chain: C
Length: 89 amino acids
Theoretical weight: 10.4 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: O94742 (Residues: 1-89; Coverage: 100%)
Gene names: DSH1, SEM1, YDR363W-A
Sequence domains: DSS1/SEM1 family

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 5.3Å
Relevant EMDB volumes: EMD-3440
Expression system: Spodoptera frugiperda