5fxi

Electron Microscopy
6.4Å resolution

GluN1b-GluN2B NMDA receptor structure in non-active-2 conformation

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Glutamate receptor ionotropic, NMDA 1 Chains: A, C
Molecule details ›
Chains: A, C
Length: 846 amino acids
Theoretical weight: 95.22 KDa
Source organism: Rattus norvegicus
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P35439 (Residues: 23-190, 191-847; Coverage: 90%)
  • Best match: P35439-7 (Residues: 23-868)
Gene names: Grin1, Nmdar1
Sequence domains:
Glutamate receptor ionotropic, NMDA 2B Chains: B, D
Molecule details ›
Chains: B, D
Length: 827 amino acids
Theoretical weight: 92.93 KDa
Source organism: Rattus norvegicus
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q00960 (Residues: 27-852; Coverage: 57%)
Gene name: Grin2b
Sequence domains:

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 6.4Å
Relevant EMDB volumes: EMD-3354
Expression system: Spodoptera frugiperda