5ffz

X-ray diffraction
2.58Å resolution

S. aureus MepR bound to ethidium bromide

Released:
Source organism: Staphylococcus aureus
Entry authors: Birukou I, Newman CE, Brennan RG

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
HTH marR-type domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 140 amino acids
Theoretical weight: 16.26 KDa
Source organism: Staphylococcus aureus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q5Y812 (Residues: 2-139; Coverage: 99%)
Gene names: A7U51_0372, BN1321_80052, BSG38_01965, DD547_00321, DQV53_02015, E3A28_07080, E3K14_01680, E4U00_07045, E5491_01630, EP54_02880, EQ90_08705, ER624_08545, ERS365775_01102, FA040_06450, FPP48_02135, FVP29_16075, G6X35_08530, G6Y10_02445, G6Y24_06545, G6Y28_10025, G6Y30_16190, GO706_13580, GO788_13690, GO793_15615, GO814_10745, GO941_13505, GQX47_07520, GZ128_07230, GZ145_07680, H2623_04235, H4Q63_12340, HMPREF2819_05630, HT539_05120, HW113_02090, HYH24_00535, LG33_01790, NCTC10654_00435, NCTC10702_00659, NCTC10988_00500, NCTC5664_00388, NCTC7878_00347, RK65_005455, SA0759_02420, SA950122_02356, SABB_01515, SAJPND4_00330, SAMEA103891215_00098, SAMEA103891286_00825, SAMEA103891321_02262, SAMEA103891571_00143, SAMEA1469856_01570, SAMEA1966928_00715, SAMEA1969845_00148, SAMEA1972827_00318, SAMEA2076218_00102, SAMEA2076226_00840, SAMEA2076235_01509, SAMEA2076464_01433, SAMEA2076470_01651, SAMEA2076472_01499, SAMEA2076475_01811, SAMEA2076481_01200, SAMEA2076758_01316, SAMEA2077031_01780, SAMEA2077046_01587, SAMEA2077832_00959, SAMEA2078252_01456, SAMEA2078307_01370, SAMEA2078308_01488, SAMEA2078558_01038, SAMEA2078569_01498, SAMEA2078588_01240, SAMEA2078824_01508, SAMEA2078837_01152, SAMEA2079048_01645, SAMEA2079512_00843, SAMEA2079517_00964, SAMEA2079727_01296, SAMEA2079728_00319, SAMEA2079949_00319, SAMEA2079951_00869, SAMEA2079957_00148, SAMEA2079958_00148, SAMEA2079968_00103, SAMEA2080812_01602, SAMEA2080900_01748, SAMEA2080904_01627, SAMEA2080913_01657, SAMEA2081043_01093, SAMEA2081054_01575, SAMEA2081211_01443, SAMEA2081362_00340, SAMEA2081458_00434, SAMEA2081475_00417, SAMEA4008573_01909, SAMEA4008676_01727, SAMEA958779_00294, SAMEA958793_00444, SAMEA958804_01327, SAMEA958836_01100, SAMEA958838_00758, SAMEA958987_01171, SAST44_03215, mepR
Sequence domains: MarR family
Structure domains: Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E+ SUPERBRIGHT
Spacegroup: R32
Unit cell:
a: 119.061Å b: 119.061Å c: 56.279Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.248 0.245 0.27
Expression system: Escherichia coli