5ep2

X-ray diffraction
1.42Å resolution

Quorum-Sensing Signal Integrator LuxO - Catalytic Domain in Complex with AzaU Inhibitor

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Putative repressor protein luxO Chain: A
Molecule details ›
Chain: A
Length: 256 amino acids
Theoretical weight: 28.61 KDa
Source organism: Photobacterium angustum
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q1ZS18 (Residues: 140-387; Coverage: 52%)
Gene name: VAS14_05548
Sequence domains: Sigma-54 interaction domain
Structure domains:

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: P61
Unit cell:
a: 76.403Å b: 76.403Å c: 82.255Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.161 0.16 0.184
Expression system: Escherichia coli BL21(DE3)