X-ray diffraction
1.8Å resolution

Staphylococcus aureus Type II pantothenate kinase in complex with a pantothenate analog


Function and Biology Details

Reaction catalysed:
ATP + (R)-pantothenate = ADP + (R)-4'-phosphopantothenate
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Type II pantothenate kinase Chain: A
Molecule details ›
Chain: A
Length: 273 amino acids
Theoretical weight: 29.96 KDa
Source organism: Staphylococcus aureus subsp. aureus MW2
Expression system: Escherichia coli BL21
  • Canonical: Q2FWC7 (Residues: 1-267; Coverage: 100%)
Gene names: SAOUHSC_02371, coaA, coaW
Sequence domains: Fumble
Structure domains: Nucleotidyltransferase; domain 5

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: C2221
Unit cell:
a: 56.967Å b: 136.771Å c: 73.87Å
α: 90° β: 90° γ: 90°
R R work R free
0.171 0.169 0.207
Expression system: Escherichia coli BL21