PDBe 5eko

X-ray diffraction
2Å resolution

Crystal structure of MAPK13 complex with inhibitor

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Mitogen-activated protein kinase 13 Chain: A
Molecule details ›
Chain: A
Length: 371 amino acids
Theoretical weight: 42.63 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O15264 (Residues: 1-352; Coverage: 96%)
Gene names: MAPK13, PRKM13, SAPK4
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P212121
Unit cell:
a: 61.263Å b: 69.669Å c: 93.068Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.202 0.2 0.241
Expression system: Escherichia coli