PDBe 5ekn

X-ray diffraction
2.59Å resolution

Crystal structure of MAPK13 complex with inhibitor


Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Mitogen-activated protein kinase 13 Chain: A
Molecule details ›
Chain: A
Length: 371 amino acids
Theoretical weight: 42.63 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: O15264 (Residues: 1-352; Coverage: 96%)
Gene names: MAPK13, PRKM13, SAPK4
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 4.2.2
Spacegroup: P212121
Unit cell:
a: 61.047Å b: 70.206Å c: 92.908Å
α: 90° β: 90° γ: 90°
R R work R free
0.22 0.218 0.273
Expression system: Escherichia coli