PDBe 5e5u

X-ray diffraction
2Å resolution

Crystal structure of the complex between Carbonic anhydrase-like domain of PTPRG and Immunoglobulin domains 2-3 of CNTN6

Released:

Function and Biology Details

Reaction catalysed:
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Receptor-type tyrosine-protein phosphatase gamma Chains: A, C
Molecule details ›
Chains: A, C
Length: 264 amino acids
Theoretical weight: 30.01 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q05909 (Residues: 57-320; Coverage: 19%)
Gene name: Ptprg
Sequence domains: Eukaryotic-type carbonic anhydrase
Structure domains: Alpha carbonic anhydrase
Contactin-6 Chains: B, D
Molecule details ›
Chains: B, D
Length: 199 amino acids
Theoretical weight: 22.33 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9JMB8 (Residues: 119-316; Coverage: 20%)
Gene name: Cntn6
Sequence domains: Immunoglobulin domain
Structure domains: Immunoglobulins

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-BM
Spacegroup: P212121
Unit cell:
a: 78.641Å b: 113.53Å c: 117.046Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.17 0.168 0.217
Expression system: Escherichia coli