X-ray diffraction
2.92Å resolution

Crystal structure of the RNA-helicase Prp43 from Chaetomium thermophilum bound to ADP


Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43 Chain: A
Molecule details ›
Chain: A
Length: 714 amino acids
Theoretical weight: 81.64 KDa
Source organism: Chaetomium thermophilum var. thermophilum DSM 1495
Expression system: Escherichia coli BL21(DE3)
  • Canonical: G0RY84 (Residues: 61-764; Coverage: 92%)
Gene name: CTHT_0005780
Sequence domains:
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.1
Spacegroup: P65
Unit cell:
a: 152.211Å b: 152.211Å c: 92.766Å
α: 90° β: 90° γ: 120°
R R work R free
0.193 0.19 0.23
Expression system: Escherichia coli BL21(DE3)