5c6s

X-ray diffraction
1.3Å resolution

Human Bromodomain and PHD Finger Containing 1, PWWP domain in complex with XST005904a

Released:
Source organism: Homo sapiens
Entry authors: DONG A, DOBROVETSKY E, MADER P, Santhakumar S, TEMPEL W, Arrowsmith CH, Edwards AM, BROWN PJ, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Peregrin Chain: A
Molecule details ›
Chain: A
Length: 130 amino acids
Theoretical weight: 15.08 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P55201 (Residues: 1079-1207; Coverage: 11%)
Gene names: BR140, BRPF1
Sequence domains: PWWP domain
Structure domains: SH3 type barrels.

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CLSI BEAMLINE 08ID-1
Spacegroup: P43212
Unit cell:
a: 44.453Å b: 44.453Å c: 125.877Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.194 0.194 0.217
Expression system: Escherichia coli BL21(DE3)