5c04

X-ray diffraction
1.45Å resolution

Crystal structure of the F37H mutant AhpE from Mycobacterium tuberculosis

Released:

Function and Biology Details

Reaction catalysed:
Mycoredoxin + ROOH = mycoredoxin disulfide + H(2)O + ROH
Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Alkyl hydroperoxide reductase E Chains: A, B
Molecule details ›
Chains: A, B
Length: 153 amino acids
Theoretical weight: 16.84 KDa
Source organism: Mycobacterium tuberculosis
Expression system: Escherichia coli
UniProt:
  • Canonical: P9WIE3 (Residues: 1-152; Coverage: 99%)
Gene names: MTCY427.19c, Rv2238c, ahpE
Sequence domains: AhpC/TSA family
Structure domains: Glutaredoxin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SOLEIL BEAMLINE PROXIMA 1
Spacegroup: P43212
Unit cell:
a: 63.3Å b: 63.3Å c: 159.45Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.167 0.166 0.198
Expression system: Escherichia coli