5bn0

X-ray diffraction
2.8Å resolution

A new HIV fusion peptide inhibitor

Released:
Entry author: Xue Y

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Transmembrane protein gp41 Chains: C, D
Molecule details ›
Chains: C, D
Length: 37 amino acids
Theoretical weight: 4.49 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Not provided
UniProt:
  • Canonical: P04578 (Residues: 627-661; Coverage: 4%)
Gene name: env
Transmembrane protein gp41 Chains: B, E, N
Molecule details ›
Chains: B, E, N
Length: 36 amino acids
Theoretical weight: 4.13 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Not provided
UniProt:
  • Canonical: P04578 (Residues: 546-581; Coverage: 4%)
Gene name: env
Transmembrane protein gp41 Chain: A
Molecule details ›
Chain: A
Length: 36 amino acids
Theoretical weight: 4.47 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Not provided
UniProt:
  • Canonical: P04578 (Residues: 627-661; Coverage: 4%)
Gene name: env

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007 HF
Spacegroup: C2
Unit cell:
a: 77.15Å b: 52.34Å c: 60.26Å
α: 90° β: 117.46° γ: 90°
R-values:
R R work R free
0.272 0.271 0.288
Expression system: Not provided