PDBe 5a6u

Electron Microscopy
9Å resolution

Native mammalian ribosome-bound Sec61 protein-conducting channel in the 'non-inserting' state

Released:
Source organism: Canis lupus familiaris
Related structures: EMD-3068

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Protein transport protein Sec61 subunit alpha isoform 1 Chain: A
Molecule details ›
Chain: A
Length: 451 amino acids
Theoretical weight: 49.32 KDa
Source organism: Canis lupus familiaris
UniProt:
  • Canonical: P38377 (Residues: 26-476; Coverage: 95%)
Gene name: SEC61A1
Sequence domains:
Protein transport protein Sec61 subunit beta Chain: B
Molecule details ›
Chain: B
Length: 36 amino acids
Theoretical weight: 3.99 KDa
Source organism: Canis lupus familiaris
UniProt:
  • Canonical: P60467 (Residues: 61-96; Coverage: 38%)
Gene name: SEC61B
Protein transport protein Sec61 subunit gamma Chain: G
Molecule details ›
Chain: G
Length: 62 amino acids
Theoretical weight: 7.02 KDa
Source organism: Canis lupus familiaris
UniProt:
  • Canonical: P60058 (Residues: 7-68; Coverage: 91%)
Gene name: SEC61G
Sequence domains: SecE/Sec61-gamma subunits of protein translocation complex

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution:
Relevant EMDB volumes: EMD-3068