PDBe 5a6e

Electron Microscopy
4.5Å resolution

Cryo-EM structure of the Slo2.2 Na-activated K channel

Released:
Source organism: Gallus gallus
Related structures: EMD-3062

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
S1-S4 DOMAIN OF POTASSIUM CHANNEL SUBFAMILY T MEMBER 1 Chain: A
Molecule details ›
Chain: A
Length: 139 amino acids
Theoretical weight: 11.85 KDa
Source organism: Gallus gallus
Expression system: Spodoptera frugiperda
Potassium channel subfamily T member 1 Chain: B
Molecule details ›
Chain: B
Length: 94 amino acids
Theoretical weight: 10.72 KDa
Source organism: Gallus gallus
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q8QFV0 (Residues: 244-337; Coverage: 8%)
Gene names: KCNT1, SLACK
Sequence domains: Ion channel
Potassium channel subfamily T member 1 Chain: C
Molecule details ›
Chain: C
Length: 700 amino acids
Theoretical weight: 79.32 KDa
Source organism: Gallus gallus
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q8QFV0 (Residues: 351-1019; Coverage: 56%)
Gene names: KCNT1, SLACK
Sequence domains: Calcium-activated BK potassium channel alpha subunit
RCK2 ELABORATION OF POTASSIUM CHANNEL SUBFAMILY T MEMBER 1 Chain: D
Molecule details ›
Chain: D
Length: 43 amino acids
Theoretical weight: 3.68 KDa
Source organism: Gallus gallus
Expression system: Spodoptera frugiperda

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 4.5Å
Relevant EMDB volumes: EMD-3062
Expression system: Spodoptera frugiperda