X-ray diffraction
1.81Å resolution

Crystal structure of T75S mutant of Triosephosphate isomerase from Plasmodium falciparum


Function and Biology Details

Reaction catalysed:
D-glyceraldehyde 3-phosphate = glycerone phosphate
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Triosephosphate isomerase Chains: A, B
Molecule details ›
Chains: A, B
Length: 248 amino acids
Theoretical weight: 27.98 KDa
Source organism: Plasmodium falciparum
Expression system: Escherichia coli
  • Canonical: Q07412 (Residues: 1-248; Coverage: 100%)
Gene name: TPI
Sequence domains: Triosephosphate isomerase
Structure domains: Aldolase class I

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P21
Unit cell:
a: 39.23Å b: 76.54Å c: 74.94Å
α: 90° β: 98.27° γ: 90°
R R work R free
0.178 0.175 0.237
Expression system: Escherichia coli